New Instrumentation For Three-Step Follicular Unit Extraction

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When we published the technique of Follicular UnitThe incidence of buried grafts can be reduced by
Extraction (FUE) in 2002, Dr. Rassman and Iavoiding the nuchal area (the lower part of the
described a two-step process for this new hairscalp) where the angle of the hair is very acute
transplant procedure.[1] The first step was to useand the skin has more resistance to the punch.
a sharp, circular instrument to separate theAnother trick is to clip the hair very short (less
follicular units from the surrounding tissue and thenthan 1-mm) before extracting, as a trapped hair
to remove them from the scalp using finewill push the graft deeper into the scalp. One can
forceps. The success of the hair restorationalso make the sharp cut slightly deeper and the
varied from patient to patient, so we developed adull dissection more superficial. On occasion,
simple test (The FOX Test) to see which patientschanging the angle of both the sharp and/or blunt
were good candidates for this type of procedure.instrument can minimize the incidence of buried
Hair transplant patients that were FOX 1 hadgrafts. Reverting back to a two-step procedure
virtually no transection (damage) to follicles duringworks well in select hair transplant patients,
their removal and those with lower FOX ratingsparticularly those with very coarse hair. Finally,
exhibited more transection, with FOX 5 patientsyou can optimize the blunt tip design.
having excessive damage during theNew Instrument Design
extraction.[1,2]We looked at a number of different designs for
The three-step technique for Follicular Unitthe blunt-edged instrument. The first design we
Extraction (FUE) is based upon Dr. Harris's concepttried was a beveled edge. When beveling the
of using a blunt instrument to prevent damage toedge inward, we found that the constricting lumen
follicles during the process of separating thepushes down on the graft, so this clearly was not
follicular unit from the surrounding donor tissue.the answer. We tried placing the bevel on the
The three steps are: 1) scoring-using a sharpoutside surface, but the width of the wall was a
punch, 2) blunt dissection - using a dull instrument,problem with this configuration as well.
and 3) extraction - using fine forceps.[3,4] TheGoing back basics, we tried a more simple design
three-step procedure decreased the amount of- a cylindrical tube. It was easy to make, the
transaction in virtually all hair restoration patientsedge didn't wear down, and it was reusable. The
and thus enabled a greater number to beproblem with a cylinder, however, was that the
classified as FOX 1. However, the three-stepflat edge also pushed the grafts into the
procedure introduced a new problem with FUE,subcutaneous space. We tried to vary the wall
that of buried grafts.[4]thickness with the idea was that if the wall of a
Why Use a 3-Step Technique?simple cylinder was thin enough; it could dissect
The need for the three-step procedure has twothe follicular unit from the surrounding tissue
basic anatomic underpinnings. The first is that thewithout pushing the grafts into the fat. The
angle of the hair that sticks out above theproblem was that these instruments were too
surface of the skin is not the same as the anglefragile.
of the hair follicle below the skin's surface. InWe added a bull nose edge to one end of the
addition, the angles differ from follicle to follicle.cylinder with the idea that a rounded edge would
Therefore, it is literally impossible to exactly alignmake blunt dissection possible without the
the cutting instrument with the hair follicle as itnecessity of having to make the wall too thin. We
passes into the depths of the dermis.used two techniques to create this rounded edge.
The second issue is that, although the follicles inOne was an acid bevel (also called electro-polish)
the follicular units are gathered or grouped on thewhich made only a minor modification to the edge.
surface and in the mid-dermis, as they sit deeperThe second, was the more conventional
into the skin they spread outward so that by themechanical grind and polish. This turned out to be
time they enter the subcutaneous fat, they thenthe technique of choice for the manufacturing of
become random. Therefore, a cutting instrumentthe tool.
that easily fits around the follicular unit on theThe next step was to try to determine the
surface of the skin will cut off the root of theappropriate internal and external diameter. We
follicles as it passes into the fat.used a one-millimeter Miltex punch for the scoring
A solution to the problem is to use an instrumentstep (the 1-mm Miltex punch is actually a 0.9mm
that would pass around the follicular units andOD punch). For the blunt dissection phase, we
essentially gather up the follicular bulbs that arefound that a larger punch would fit into the
spread out in the fat3. We used a prototypeopening of the scored area, since the skin that
instrument that could be used for the bluntwas separated from the graft stretched to make
dissection step and we examined forty hairthe hole slightly wider.
transplant patients in our study to confirm thisWe found an internal diameter of 1.37 mm to be
hypothesis. We looked at twenty graftsoptimal for the blunt instrument, as this fit nicely
extracted from the donor area of each patient.around the top of the scored follicular unit and
One side was done with two-step FUE and thecould accommodate units of up to 4-hairs. With
opposite side with three-step FUE. Using aan outside diameter of 1.5mm, the instrument
stereo-microscope at 10X, we evaluated the sizewould have a wall width of 0.064mm (2.5
of the follicular units and the amount of folliclesthousandths of an inch) that was thick enough to
lost through transection.give the instrument stability, yet still small enough
In interpreting the results, one first needs toto fit into the wound.
define a few terms. The graft yield is simply theWe inserted the notched end into a Versi handle
number of grafts versus the number ofwith about seven millimeters of the blunt-tipped
attempted extractions. This is actually a deceptiveend exposed. One can shorten this end to 4- or
number because if you extract only one hair from5-mm and use the handle as a "stop" i.e. a depth
a multi-haired follicular unit that would still be calledcontrol, but it makes it slightly more difficult to
a graft (this convention is used by many haircontrol the angle.
transplant doctors performing FUE). What is moreInstrument for Follicular Unit Extraction (FUE)
valuable information is hair yield. The hair yield isFigure 9. Cylindrical Punch in Versi-Handle.
the number of intact hairs obtained versus theWe found that the incidence of buried grafts
total numbers of hairs in the follicular unit that onedecreased significantly with the new instrument -
is attempting to extract. (Figure 5)from about 9 percent to 1.8 percent with the
As an example, in a case where only one intactnew device. However, we still found significant
hair was obtained from a 3-hair follicular unit, thevariability between hair restoration patients,
graft yield would be 100 percent, whereas themaking pre-procedure testing (Fox Test) still
hair yield (which is really the more importantuseful.
measurement) would be only 33 percent.Conclusion
The results of this study showed that for thePerforming Follicular Unit Extraction with a 3-step
two-step technique the graft yield wastechnique allows the hair restoration surgeon to
reasonable, 92 percent, but the hair yield is onlyminimize follicular transection and keep follicular
74 percent. With the three-step procedure, it wasunits intact. A disadvantage of the 3-step
98 percent and 93 percent respectively, so theretechnique over a 2-step process is the increased
was a really significant improvement with theincidence of buried grafts. This can be reduced by
three-step technique in maintaining intact hairmodifying ones extraction techniques and using an
follicles.instrument that is specifically designed to facilitate
Although this three-step procedure is superior tothe blunt-dissection step of the process. The
a two-step procedure in avoiding follicularthree-step technique, using customized
transection and in preserving follicular units, thereinstrumentation to avoid transection, is just one
was a greater incidence of buried grafts.more step in the evolution and refinement of FUE.
Buried GraftsReferences
Buried grafts occur when grafts are inadvertently1. Rassman WR, Bernstein RM, McClellan R, Jones
pushed into the subcutaneous tissue during FUE.R, et al. Follicular Unit Extraction: Minimally invasive
These grafts can be left alone, but they maysurgery for hair transplantation. Dermatol Surg
develop into cysts that would eventually need to2002; 28(8): 720-7.
be removed. If they're not completely buried, the2. Bernstein RM, Rassman WR, Anderson KW:
grafts can sometimes be extracted using a smallFollicular Unit Extraction Megasessions: Evolution of
instrument called a Shamberg extractor (thea technique. Hair Transplant Forum International
instrument used by dermatologists to remove2004; 14(3): 97-99.
black-heads). In the more common situation, you3. Harris JA. The SAFE System: New
must extend the incision slightly so that the buriedInstrumentation and Methodology to Improve
graft can be grasped with forceps. We use a No.Follicular Unit Extraction (FUE). Hair Transplant
11 scalpel blade for the incision. Removing buriedForum Intl. 2004; 14(5): 157, 163-4.
grafts, although not difficult, is extremely4. Rassman WR, Harris J, Bernstein RM. Follicular
time-consuming. If one has a buried graft rateUnit Extraction. In Stough-Haber 2005 (Accepted
over a fraction of a percent, it becomes afor Publication).
significant logistical problem for the hair transplant