| Since the publication of a book called 'Beat Chronic | | | | have a beneficial action on the chemical |
| Fatigue The Natural Way', many people are | | | | imbalances in the brain which we have identified." |
| turning to the natural substance omega 3, and in | | | | Since this study was published further advances |
| particular pure ethyl EPA, to help treat the | | | | have been made, and the findings released by a |
| debilitating condition known as chronic fatigue | | | | leading professor in the United Kingdom state |
| syndrome. | | | | clearly that he considers Chronic Fatigue |
| What is chronic fatigue syndrome ? | | | | Syndrome to be a genuine physical illness. The |
| We all get tired. Many of us have felt depressed | | | | professor describes how he came to conclude |
| at times. But the mysterious chronic fatigue | | | | that CFS could be successfully treated by |
| syndrome (CFS) is not like the normal ups and | | | | supplementation with essential fatty acids, |
| downs we experience in everyday life. The early | | | | specifically ultra-pure EPA (eicosapentaenoic acid) |
| sign of this illness is a strong and noticeable | | | | and virgin evening primrose oil. |
| fatigue that comes on suddenly and often comes | | | | The professor describes the changes in the |
| and goes - sometimes, it never stops. You | | | | immune system seen with CFS, as a reduction in |
| sometimes feel too tired to do normal activities | | | | natural killer cell activity and a shift from TH1 cell |
| or are easily exhausted with no apparent reason. | | | | activity toward increased TH2 cell activity, known |
| Unlike the mind fog of a serious hangover, to | | | | as a type 2 immune response. He believes that |
| which researchers have compared CFS, the | | | | this is best explained by the presence of a |
| profound weakness of CFS does not go away | | | | pre-existing, long-term, viral infection to which the |
| with a few good nights of sleep. Instead, it slyly | | | | immune system is reacting. Using MRI scanning to |
| steals your energy and vigour over months and | | | | carry out neurospectroscopy examinations of |
| sometimes years. | | | | people with CFS, in order to obtain information |
| Who gets chronic fatigue syndrome? | | | | about the chemistry of the living brain, the |
| Chronic fatigue syndrome (CFS) affects both men | | | | professor demonstrated a clear difference |
| and women, and its incidence cuts across wide | | | | between the brains of people with CFS and |
| strata of age as well as racial and socio-economic | | | | ‘normal' volunteers; the results indicated a |
| groups. It was first described in the 1930s; CFS | | | | very significant change in the turnover of fatty |
| received a flurry of publicity in the mid-1980s | | | | acids in the cell membranes of CFS sufferers. |
| when the syndrome was erroneously associated | | | | Essential fatty acids - linoleic acid (omega-6) and |
| with the Epstein-Barr virus. In the early to | | | | alpha linolenic acid (omega-3) - are known as such |
| mid-1990s it was being described as 'yuppie flu'. | | | | because they must be acquired from food and |
| Symptoms of chronic fatigue syndrome | | | | cannot be manufactured by the body. The |
| * muscle aches and pains, especially after physical | | | | professor explains how viruses can cause the |
| exertion | | | | symptoms of CFS by inhibiting a crucial enzyme in |
| * feeling depressed and emotional | | | | the chains that convert these essential fatty acids |
| * poor sleep, difficulty getting off to sleep, | | | | into other fatty acids required by the body, |
| frequent wakings, and not feeling refreshed after | | | | including GLA (gamma-linolenic acid), EPA and DHA |
| sleep | | | | (docosahexaenoic acid). This leads to a deficiency |
| * nausea and loss of appetite | | | | in these fatty acids. He believes the resulting lack |
| * a recurrent sore throat, feeling of enlarged | | | | of EFAs in the body leads to many of the |
| glands in the neck which come and go | | | | symptoms familiar to CFS sufferers, including |
| * running a slightly high temperature for no | | | | tiredness, poor immune response and painful |
| apparent reason | | | | joints. |
| * feeling of faintness and dizziness | | | | The professor concluded by saying that by giving |
| Omega 3 fish oil EPA and chronic Fatigue | | | | patients large amounts of GLA and EPA the |
| syndrome | | | | effects of the virus can be circumvented and |
| The most recent study that has been performed | | | | how CFS patients taking high-dose supplements |
| was published in the journal Acta Psychiatrica | | | | reported improvements in symptoms within 12 |
| Scandinavica. In the study, doctors from London | | | | weeks. Crucially, the supplement should be |
| found that in the brains of people with chronic | | | | DHA-free, which means that the majority of fish |
| fatigue syndrome there are high levels of two | | | | oil supplements, which contain both EPA and DHA, |
| key chemicals, choline and creatine. | | | | are not suitable. The Professor also strongly |
| Choline is important for controlling fat levels in | | | | believes that the type of DHA found in most fish |
| brain cells while creatine provides energy. | | | | oil supplements inhibits some of the beneficial |
| The doctors said the findings suggested CFS | | | | actions of EPA. |
| patients had abnormal phospholipid metabolisms. | | | | Conclusion |
| Phospholipids are special types of fats which are | | | | Since both these sets of findings were released, |
| an essential component of cells. They are | | | | more and more people are turning to high grade |
| protected by certain types of fatty acids. | | | | ethyl EPA fish oil to help with this debilitating |
| The London doctors believed fatty acid | | | | condition. Whether this will lead to a mainstream |
| supplements could help to restore the chemical | | | | treatment for chronic fatigue syndrome, and |
| imbalance in the brain and alleviate the symptoms | | | | whether it will work for all sufferers, remains to |
| of CFS. EPA, which is found in omega 3 fish oil | | | | be seen. However, a large majority of people |
| supplements, may be particularly useful. | | | | who are trying this as a form of treatment are |
| The leader of the study said: "This study | | | | reporting some very interesting and very good |
| suggests that if patients with CFS take a | | | | results. |
| high-EPA fatty acid supplement, then this should | | | | |