Understanding Chronic Fatigue Syndrome and Fibromyalgia

Relative to many of today's diseases andand mood disorders, and lowered levels of the
disorders, little is known about the etiology, theneurotransmitters norepinephrine and serotonin,
cause, and the long-term effects of Chronicalso with an impact on mood and pain, to include
Fatigue Syndrome (CFS) and Fibromyalgianeck pain, back pain, deep hip and pelvis pain, and
Syndrome (FMS). The two disorders share asciatica. Fibromyalgia sufferers in particular
myriad of characteristics, however, which begsexperience a decreased threshold for pain overall,
the question: Are they really two separateat times localized and at other times diffuse and
diseases? How does Myofascial Pain Syndrome fitacute. Chronic fatigue patients will also suffer
in? What are the various pain expressionsfrom idiosyncratic pain, diffuse and varied in its
characteristic of each? How are symptoms theexpression. Abnormalities also arise in each of the
same or distinct from each other? Neck pain,nervous system's two branches, the sympathetic
back pain, and sciatica have been reported in alland parasympathetic nervous systems.
three conditions but in varying degrees ofFMS and CFS patients may also exhibit disorders
intensity and frequency. How are they the sameaffecting multiple body systems, the nervous
and how are they different? We have alreadysystem, as noted above, the circulatory system,
begun to explore the answers to these questionsparticularly hypertension and heart-related
in previous articles, we will continue to do so inproblems (also a possible stress link) and digestive,
this and subsequent articles in this series.as in ulcers and acid reflux (stress again) and
There are many similarities between chronicendocrine (hormones also impacted by stress).
fatigue syndrome and fibromyalgia. The course ofSleep abnormalities are considerable and
both disorders is generally persistent and chronic,widespread. Interestingly, brain imaging seems to
with symptoms arising steadily to a crescendo,indicate that blood flow wanes to some areas of
often waxing and waning in cycles. Unfortunately,the brain. Symptoms also appear to arise in
the prognosis is poor with little real understandingpatients' sensory processing, generating a higher
of the etiology or cause. Treatment strategies forsensitivity to sensory input (light, sound, chemicals)
both chronic fatigue and fibromyalgia are focusedand, again, pain stimuli. To summarize, chronic
more on symptoms than on treating thefatigue syndrome and fibromyalgia share a host
perceived cause. Pain often varies from dull toof symptoms, ranging from neurological to
acute, from fleeting to constant or chronic.gastrointestinal.
Improvement is possible for those with theThere are symptoms characteristic of each
disorder(s), but complete recovery is rare. Mostdisease or disorder, chronic fatigue and
CFS and FMS sufferers continue to havefibromyalgia. For example, CFS presents a more
symptoms for years, if not decades.powerful association or link with intolerance to
Sufferers of both CFS and FMS also seem to beexercise, greater fatigue, flu-like symptoms and
susceptible to secondary psychological problems,vision changes. Symptoms found to be more
such as depression, anxiety, and mood swings.prevalent in fibromyalgia include the presence of
The psychological and psychosomatic aspects ofthe particularly painful trigger and tender points
these conditions have not been lost onand the presence of allodynia. Allodynia is the
researchers, with much current research focusingpowerful triggering of pain responses for things
on related psychological issues. It is also quitethat wouldn't be painful to an unaffected person.
common for depression to become quite serious,Physicians refer to a certain pain expression from
as chronic fatigue symptoms and fibromyalgia painmovement or motion as "motion allodynia." Pain
take a heavy toll.specialists refer to pain at a comfortable or
Treatment for both disorders, FMS and CFS, arenormal temperature, temperature not
often similar, if not the same. Increaseduncomfortable to the most people, as "cold
occurrence has been demonstrated in bloodallodynia." Allodynia is often used by physicians to
relatives, suggesting a possible genetic componentrefer to neuropathic or "bizarre" pain, which
to the disorder. And, while certain segments ofpresents as the result of any non-noxious stimuli,
the population seem to be at greater risk, areoften "jumping around from affected to
more susceptible, both conditions are present in allunaffected parts of the body.
demographic groups. However, the mostOf the two disorders, CFS is being reported to be
susceptible demographic group, for both disorders,nearing or at epidemic levels, affecting many
is women in their middle years, particularly womenpersons at the same time across a wide range of
from 30 to 50 years of age. Symptoms of bothdemographic groups. CFS symptoms wax and
fibromyalgia and chronic fatigue syndrome seemwane more frequently than symptoms of FMS,
to worsen after exertion, demanding activity, andand the rate of disability is greater in chronic
stress of all types (physical, cognitive or emotion).fatigue syndrome patients. Currently, we don't
When routine lab tests are conducted on patientsknow what the direct (or indirect) connection is
with suspected CFS or FMS, the results quitebetween chronic fatigue syndrome and
often appear normal. Both disorders arefibromyalgia. Early research and speculation has
extremely difficult to diagnose. CFS and FMSsuggested that they could possibly be distinct,
often overlap or are found jointly with othermeaning the two disorders are not related,
disorders and/or diseases such as allergies, tensionidentical, the same disorder, but with different
headaches, migraines, irritable bladder, irritablenames, overlapping, two diverse expressions of a
bowel and autoimmune disorders.similar disorder or possibly the result of different
Chronic fatigue and fibromyalgia also sharecauses or triggers leading to a common pathway,
numerous abnormalities not commonly linked totwo subtypes of a larger illness and part of a
other disorders. Some of the abnormalities orspectrum of illnesses, including both...and possibly
characteristics peculiar to CFS and FMS includeMyofascial Pain Syndrome. Until further research is
central nervous system abnormalities (CNS),done, it is difficult to say with any degree of
perhaps a reason for the various pain expressionscertainty.