CBC
w/diff & Platelet Ct.: This "panel"
measures several parameters in peripheral blood, e.g.
white and red blood cells. In addition, a WBC differential
is preformed along with a measure of platelets.
Cell
Dysregulation: Through the use of flow cytometry,
different populations of white blood cells are counted
and evaluated for function.
HLA-Dr
Typing: Human lymphotropic antigen is found on the
surface of B lymphs and in monocytes. Often used as
a gauge to predict successful tissue transplants.
Pneumococcal
Antibody: A member of the Strep genus they are found
in normal throat cultures but are the primary cause
for bacterial pneumonia. Antibody response is directed
against these organisms.
Natural
Killer Cell Functional Assay: Measures and evaluates
"special" lymphocytes responsible for cell
lysis in vivo. Part of the "T" cell family
they are associated with several disease entities.
DHEA
sulfate: A metabolite of DHEA, this androgen is
produced in the adrenal glands and is a measure of adrenal
function.
Carotene:
Fat-soluable precursor of Vitamin A, carotene is primarily
obtained through diet.
Magnesium/Potassium/Calcium,
RBC: RBC's contain 2 - 3 times the amount of these
elements than does serum. Levels in RBC's measured as
an adjunct to serum evaluation to determine overall
concentration in the body.
Herpes
6 Virus: HHV6 infects primarily the "T"
lymphs of the CF4 (helper) type. Antibodies to this
6th described member of the herpes family are commonly
found in most children and adolescents.
Febrile
Agglutinins: Serologic tests for organisms causing
fever, e.g. thyphoid fever.
Interleukin-2(IL-2):
Produced by lymphocytes, IL-2 is elevated in certain
diseases, e.g. Rheumatoid Arthritis, SLE, type I diabetes
and others. Measurement may be used in response to therapy.
Angiotensin-1-Converting
Enzyme: is found in lung epithelial cells. Its primary
function is to convert angiotensin I to the vasoconstrictor
angiotensin II. Elevations are seen in active sarcoidosis.
IgG: Immunoglobulin "G" comprises about
75% of the total immunoglobulins and is the fraction
containing most antibodies.
Coxsackie
Virus (group A/B): An enterovirus, coxsackie virus
is among the most common causes for viral meningitis
(up to 80% of cases.)
Lyme
AB: This antibody is formed in response to the Tick-borne
organism Borrelia Borgdorferi, the causative agent for
Lyme disease>
EBV:
Epstein Barr virus antibodies are directed against EBV,
a herpes-group virus reported to infect 80% of the US
population. Infected young children are usually asymptomatic:
older children and adults develop Infectious Mono syndrome.
EBV is also associated with Burkitt's lymphoma in Africa
and nasopharyngeal carcinoma in Southern Chile.
CMV:
Cytomegalovirus, also a herpes group virus affects mostly
children and adolescents. Largely asymptomatic, CMV-infected
individuals resemble those infected with EBV. The virus
is shed in body secretions, eg. saliva, semen and urine.
FANA:
The fluorescent test for antinuclear antibodies (also
referred to as an LE test) measures the level of various
antibodies in serum detected against different cell
nuclei. Presence of ANA's correlates with the number
of immunologic conditions, eg. Sjrogen's, lupus and
other collagen diseases. The nuclear staining pattern
is reported.
ANTI-ds
DNA: Double-stranded DNA antibodies are specific
response for SLE.
Cold
Agglutinins: IgM antibodies usually directed against
red cell antigens. Present in auto-immune conditions.
IgE:
Immunoglobulin "E" is commonly associated
with an allergic response when it is found to be elevated.
Magnesium:
Fourth most common cation; about one-half is found in
soft tissue and muscle with the other half in bone.
Mostly obtained from diet; important in protein synthesis
and enzyme activation.
Zinc:
A common component of certain enzymes, this element
is obtained primarily from food. Deficiencies can cause
growth retardation.
Calcium:
Third most common cation, calcium is a standard for
thyroid function.
T4,Free/Total
& T3U: Thyroid testing is used to assess thyroid
dysfunction and/or thyroid disease. Direct measure of
thyroxine (total & free) or triidothyronine (T3)
and indirect measure of function using FT4 index or
T3 uptake allow for supportive evidence of clinical
findings.
TSH:
Elevated thyroid stimulating hormone, now referred to
as Thyrotropin is useful in the determination of primary
thyroid disease and is found elevated in 95% of hypothyroid
patients.
Anti-thyroglobulin
AB (ATA): Autoantibody directed against a protein
produced by thyroid cells. Positive in chronic thyroiditis.
Anti-thyroid
Perox/Microsomal ABS: Autoantibodies direct against
the microsomal component of thyroid cells. More commonly
found in chronic thyroiditis than ATA.
* This test is not to be considered
as an absolute diagnostic marker for CFS. It is used
merely as a diagnostic guideline to help the physician
to assess the patient's condition.
Other Tests Available
Amino Acid Profile - Aatron Labs
HHV6 Rapid Culture - Herpesvirus Diagnostics
Mycoplasma - Immunosciences Lab
Mycoplasma - Dr. Garth Nicolson's Lab
Lyme Disease by PCR - Medical Diagnostic Labs